The SICRIT® source can be directly coupled to the transfer line from a GC, enabling the eluting compounds from the GC to be ionised and detected in an existing LC-MS. The ion source acts as a direct connector between chromatography and the MS detector allowing combination of any chromatograph with any MS system. In this way, analyte molecules of a broad polarity range are softly ionised during transfer in the MS inlet. As a consequence, SICRIT® is dedicated for powerful GC-soft ionisation-MS analysis, where MS instruments originally built for LC-MS applications can be utilised for GC-MS measurements. This new instrument combination provides MS data, which can be directly matched to the LC-MS data acquired on the same instrument.