Partners in Progress

MALDI Atmospheric Pressure Mass Spectrometry

The Atmospheric-Pressure Matrix-Assisted Laser-Desorption Ionisation (AP-MALDI) source enables mass spectrometers fitted with an electrospray or nanospray source to have the additional capability of MALDI. It is called AP-MALDI because, unlike vacuum MALDI, ionisation takes place under atmospheric conditions. This provides several important advantages including convenience, speed of analysis, simplicity of operation and cost

Features

• Change between MALDI and ESI/nanospray in minutes. Calibrate in ESI and switch to MALDI without recalibration. Sample plates loaded in seconds as there is no waiting for vacuum to be achieved
• MS-MS and MSⁿ data (if instrumental capabilities permit) from a MALDI source for enhanced sequencing information at a fraction of the cost of a TOF-TOF instrument
• Robotic control of MALDI targets with CCTV point-and-click visual alignment checking for confidence in operation
• Imaging acquisition and processing software for MALDI-imaging of tissues and other surfaces
• Can be fitted to instruments from Thermo, Bruker, Agilent, ABI, Varian and JEOL

Nd-YAG Laser

• Third-generation versions of the AP-MALDI source are fitted with the new all solid-state Nd-YAG laser.
• Integrated pulsed-dynamic-focussing (PDF) for maximum sensitivity
• All solid-state Nd-YAG laser guaranteed for 1 billion firings for increased reliability and low cost-of-ownership
• Up to 200 Hz repetition rate for higher throughput and faster imaging
• Software-controlled attenuation for more reproducible analyses

New Tuneable IR Laser

IRIS - Infra-Red Ionisation from Solution

• 2 tunable wavelength options
• 1 mJoule pulse energy
• Choice of 20 or 100 Hz repetition rates
• Optional UV wavelength output in same unit
• Software controlled energy attenuation