The data to the right was produced using an AP‑MALDI / Orbitrap MS imaging experiment performed by Dr. Gilles Frache, Luxembourg Institute of Science and Technology / Materials Research and Technology (MRT). The mouse brain was obtained through the courtesy of Dr. M. Buttini, Luxembourg Centre for Systems Biomedicine. The tissue was imaged using the MassTech AP-MALDI source connected to a ThermoFisher Scientific Orbitrap Elite XL.
One of the uses of MALDI tissue imaging in the pharmaceutical industry is to monitor the distribution of drugs and their metabolites in target tissues. This interesting application note shows the use of the AP-MALDI source with a high resolution mass spectrometer analysing tissues that have been prepared for analysis using the SunCollect spraying device.